Summit Elderberry Immune Support w/Vitamin C

●  Supports immune health via increased oxidant, free radical scavenging, and fueling neutrophilic (immune cell) activity in chemotaxis, phagocytosis, and microbial killing (97,98).

●  Supports fat burning by increasing carnitine biosynthesis (molecule required for mitochondrial fatty acid oxidation) (97,98).

●  Supports accelerate bone healing after a fracture, increase type I collagen synthesis, and reduce oxidative stress (inflammation) (98).

●  Supports immune health via neutralizing free radicals and reactive oxygen species, and increased T lymphocyte-mediated immune function (204).

●  Supports cardiovascular health via reduced cholesterol (204).

●  Supports cognitive function via reduced oxidative stress, inflammation, and DNA damage of neuronal tissues (208).

●  Supports stimulation of the innate and adaptive immune system (172,173).

●  Supports the activation of lymphocytes and activation of innate and T cell mediated immunity (172,173).

●  Supports cognitive function by modulation of neuronal signaling in areas of the brain associated with memory and learning (hippocampus) (172,173).

●  Vital for lymphocyte (immune cell) proliferation (growth) and paramount in neutrophil (immune cell) destruction of bacteria (18).

●  Vital for activation of genetic signals that support immune function and vitality (18).

●  Glutamine is utilized by immune cells at high rates during catabolic conditions (post-surgery, sepsis, burns, and extreme exercise (18).

●  Supports antioxidant function due to polyphenolic content, increased free radical scavenging ability, and reduced inflammatory cytokines (231,232,233)

●  May support antiviral activity against pathogens via flavonoids that bind to and prevent H1N1-type IV infection  (234).

●  Supports antimicrobial effects  via combating bacteria that cause upper respiratory tract infections (Gram-positive bacteria Streptococcus pyogenes and group C and G Streptococci) (234).

●  Supports immune health via decreased impro-inflammatory markers (cytokines IL-6, IL-8, and TNF) (159,160).

●  Supports adaptive and innate immunity via increased monocytes, neutrophils, natural killer cells, and CD8 T cells (159,160).

●  Supports cardiovascular health via reduced hypertension, reduced total cholesterol, reduced arterial stiffness (hardening of arteries), and markers of atherosclerosis (161).

●  Supports joint health via reduced NF-κB activation (inflammation) in human fibroblasts cells and reduced prevalence of pain in individuals with rheumatoid arthritis (162).

●  Supports gut health via increased prebiotic properties, increased micro biome population, and increased Lactobacillus and Clostridia species (163).

●  Supports immune health via reduction in inflammatory markers (CRP, TNF, IL-6) (164).

●  Reduces inflammation via decreases of inflammatory markers such as c-reactive protein, interleukin 6, tumor necrosis factor, and decreased cytokine production (123).

●  Supports joint health via decreases in connective tissue inflammation and improved pain in individuals with osteoarthritis (122).

●  Supports blood sugar regulation via increased pancreatic beta cell function and improved insulin sensitivity (121).

●  Supports cardiovascular and liver health via reduced accumulation of advanced glycation end products (AGE), reduced lipid peroxidation, and improved vascular function.

●  Curcumin exhibits an antioxidant activity via scavenging of superoxide anion (∙O2−∙) and hydroxyl radicals (∙OH) (scavenging of inflammation molecules) (118,119).

●  Curcumin modulates breast carcinogenesis through its effect on cell cycle and proliferation, apoptosis, senescence, cancer spread and angiogenesis (119).

●  Curcumin targets cancer growth pathways such as the NFkB, PI3K/Akt/mTOR, MAPK and JAK/STAT. thereby suppressing tumor growth (119).

●  Supports 70% of gut-immunological axis (gut immune system) via enhanced mucosal immune response (toll-like receptors), and upregulation of genetic markers associated with macrophage (gut-immune cell) activity (108, 109).

●  Supports digestive and immune health via decreased irritable bowl symptoms, suppression of helicobacter pylori growth (pathogenic bacteria), reduced histamine (reduced allergic response), and reduced gut inflammation (103,104, 107, 108, 109).

●  Supports athletic performance via reduction of respiratory tract infections, reduced muscle damage, improved body composition, reduction lactate induced exercise (muscle burn), and body composition (108).

●  Supports gut-brain axis via increased neural, endocrine (hormonal), and anti-inflammatory modulation of the hypothalamic-pituitary-adrenal (HPA) axis (108).

●  Reduces inflammation via activation of Toll-like receptors (TLRs) and downregulates the expression of nuclear factor (NF)-κB and pro-inflammatory cytokines (inflammation markers) (109).